Though hospitalizations and other markers trended lower, the CDC received reports of 17 more pediatric flu deaths.
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People who later had or long COVID had higher resting heart rates and lower daily step counts at least 3 weeks prior to SARS-CoV-2 infection.
The reminders didn’t lead to differences in COVID-related clinical outcomes, however.
A total of 9% of placebo recipients contracted COVID-19 from a household member, compared with 3% of ensitrelvir recipients, for a 67% risk reduction.
22 studies featured patients who had been hospitalized for COVID-19.
Nine percent of people who described themselves as permanently sick or disabled had long COVID.
Lower risks for vaccinated participants were also seen when restricting the analyses to the pre-Omicron and Omicron periods, sex, age, or previous infection.
From 2021 to 2023, 23% of participants developed long-COVID symptoms, with 56% of those infected in 2021 reporting symptoms for 2 years.
German researchers say the answer may be in virus-reactive memory T cells, which are triggered by COVID infection.
If the pandemic hadn’t occurred, over half of the person-years of life lost would likely have been lived without disability, the authors say.